“Mitochondrial DNA Update
You or your members may have received an email about the update of the mitochondrial DNA database from Build 14 to Build 17, which is the most recent phylogenetic build for mtDNA. This update has been in the works for several months while the scientific team tested and verified the programming and results. We were able to release it this week, so some of you may have seen a change to your mtDNA haplogroup.
To give you an idea of the scope of this project, Build 14 was based on the analysis of 8,216 modern mitogenomes, while Build 17 was designed using 24,275 mtDNA sequences – almost three times as much information! Build 17 increased to 5437 nodes from 3550 in Build 14, an increase of 1887 haplogroups. Obviously, the update provides a much finer resolution in terms of haplogroup assignment.
In a very few cases haplogroups may have reverted to a higher branch on the tree. Usually, this is because in Build 14, some of the branches of the tree were predicted, not confirmed. The additional sequences added between Build14 and Build 17 did not provide supporting data to justify their existence, so these branches have been removed.
This update is the perfect time for those testers who have only tested mtDNA HVR1 or mtDNA Plus (HVR1 and 2) to upgrade to the Full Mitochondrial Sequence (FMS). For the next week, upgrades from mtDNA to FMS and from mtDNA Plus to FMS are only $99! Only with the FMS will testers get the full benefit of the new build, so please encourage your members to upgrade. See the upgrade page for more information and to order!”